Locke bases his moral and political philosophy on his doctrine of the ‘law of nature’. Scholars have debated the content and grounding of this law and its relationship to Christian theology. The ambiguities of the Lockean natural law’s content are traceable to an unclear grammatical construction in a crucial passage of the Treatises of Government, which can be resolved by following out a related set of arguments in that work. The ambiguities of the Lockean natural law’s grounding can then be (...) resolved by the hypothesis, strongly supported by textual evidence, that Locke relies tacitly on the reasoning of a parallel passage in Hobbes. Lockean natural law rests on neither atheistic nor specifically Christian premises but on a hypothetical natural theology. Locke’s conclusions from that natural theology represent an attempt to follow out Hobbesian logic while also tightening it up on one important point on which Hobbes himself appears to vacillate. (shrink)

Data are lacking with regard to participants' perspectives on return of genetic research results to relatives, including after the participant's death. This paper reports descriptive results from 3,630 survey respondents: 464 participants in a pancreatic cancer biobank, 1,439 family registry participants, and 1,727 healthy individuals. Our findings indicate that most participants would feel obligated to share their results with blood relatives while alive and would want results to be shared with relatives after their death.

Experiments show that psi differs from known physical processes in a variety of ways, and these differences are described herein. Because of these, psi cannot be accounted for in terms of presently known physical laws. A number of theories, of which we review a sampling, suggest ways in which known physical laws might be expanded in order to account for psi. However, there is no agreement on which of these theories, if any, will ultimately provide a general explanation. A further (...) problem in studying psi is that it is elusive, i.e., methods are not presently known by which it can be reliably produced. However, if psi is real, its study can open the door to a new frontier of knowledge and contribute to our understanding of consciousness. (shrink)

Recent models of consciousness are reviewed which explore the relationship of consciousness to physical laws; many of these also explore the relationship of consciousness to biological findings. Issues investigated by these models are discussed, with the issues framed in a general way in order to provide a comparison between the models. In Part I the issues discussed are: (1) What is the causal relationship between consciousness and the physical world (physicalism, dualism, etc.)? and (2) What physical characteristics are associated with (...) the interface between brain/physical world and consciousness? (shrink)

The term action of consciousness is used to refer to an influence, such as psychokinesis or free will, that produces an effect on matter that is correlated to mental intention, but not completely determined by physical conditions. Such an action could not conserve energy. But in that case, one wonders why, when highly accurate measurements are done, occasions of non-conserved energy (generated perhaps by unconscious PK) are not detected. A possible explanation is that actions of consciousness take place within the (...) limits of the uncertainty principle. Two models are reviewed that, using the latter assumption, propose that consciousness can originate an action potential in the brain. One (that of Eccles) uses the latter assumption only, and the other (that of Burns) additionally assumes that consciousness acts, within those limits, by ordering quantum fluctuations. (shrink)

The gastrointestinal tract is an asymmetrically patterned organ system. The signals which initiate left‐right asymmetry in the developing embryo have been extensively studied, but the downstream steps required to confer asymmetric morphogenesis on the gut organ primordia are less well understood. In this paper we outline key findings on the tissue mechanics underlying gut asymmetry, across a range of species, and use these to synthesise a conserved model for asymmetric gut morphogenesis. We also discuss the importance of correct establishment of (...) left‐right asymmetry for gut development and the consequences of perturbations in this process. (shrink)

Vacuum radiation causes a particle to make a random walk about its dynamical trajectory. In this random walk the root mean square change in spatial coordinate is proportional to t 1/2, and the fractional changes in momentum and energy are proportional to t −1/2, where t is time. Thus the exchange of energy and momentum between a particle and the vacuum tends to zero over time. At the end of a mean free path the fractional change in momentum of a (...) particle in a gas is very small. However, at the end of the mean free path each particle undergoes an interaction that magnifies the preceding change, and the net result is that the momentum distribution of the particles in a gas is randomized in a few collision times. In this way the random action of vacuum radiation and its subsequent magnification by molecular interaction produces entropy increase. This process justifies the assumption of molecular chaos used in the Boltzmann transport equation. (shrink)

The possibility of empirical test is discussed with respect to three issues: (1) What is the ontological relationship between consciousness and the brain/physical world? (2) What physical characteristics are associated with the mind/brain interface? (3) Can consciousness act on the brain independently of any brain process?

Even if all of the content of conscious experience is encoded in the brain, there is a considerable difference between the view that consciousness does independent processing and the view that it does not. If all processing is done by the brain, then conscious experience is unnecessary and irrelevant to behavior. If consciousness performs a function, then its association with particular aspects of brain processing reflect its functional use in determining behavior. However, if consciousness does perform a function, it cannot (...) be described entirely by known physical laws. Rather, even if the content of conscious experience follows physical encoding in the brain, consciousness must then be governed in part by a principle which is different from any known physical principle. (shrink)

Two forms of independent action by consciousness have been proposed by various researchers – free will and holistic processing. (Holistic processing contributes to the formation of behavior through the holistic use of brain programs and encoding.) The well-known experiment of Libet et al. (1983) implies that if free will exists, its action must consist of making a selection among alternatives presented by the brain. As discussed herein, this result implies that any physical changes mind can produce in the brain are (...) very small, and this in turn implies that holistic processing would also act to select among brain programs. The latter process would contribute to flexibility of behavior, which would therefore be an indication of the possible presence of consciousness in an animal. Because locomotion requires response to varying and unpredictable conditions, the above conclusions support the idea that simple forms of consciousness appear very early in the evolutionary line of the animal kingdom. (shrink)

Recent models of consciousness are reviewed which explore the relationship of consciousness to physical laws; many of these also explore the relationship of consciousness to biological findings. Issues investigated by these models are discussed, with the issues framed in a general way in order to provide a comparison between the models. In Part II the issues discussed include: Does all of the information content of consciousness correspond to neural coding in the brain? Does consciousness follow the brain passively, or can (...) it act independently? Is independent processing by consciousness compatible with the second law of thermodynamics? (shrink)

It is shown that if mental influence can change a position or momentum coordinate within the limits of the uncertainty principle, such change, when magnified by a single interaction, is sufficient to order the direction of traveling molecules. Mental influence could initiate an action potential in the brain through this process by using the impact of ordered molecules to open the gates of sodium channels in neuronal membranes. It is shown that about 80 ordered molecules, traveling at thermal velocity in (...) the intercellular medium in the brain, can break an ionic or covalent bond, and that the number needed to initiate an action potential is relatively small. If mental influence can act within the brain, it is reasonable to suppose it can act to some extent outside of it. If mental influence could not only order the direction of individual molecules, but coordinate this effect to produce a longitudinal pressure wave which is reasonably coherent across a macroscopic surface, only 10^4 molecules need be simultaneously affected to produce a detectible sound wave. Such an effect is not ordinarily observed, which suggests that if mental influence acts by ordering the direction of molecules, it acts at the level of individual molecules, but does not coordinate their motion. (shrink)

A new event is defined as an intervention in the time reversible dynamical trajectories of particles in a system. New events are then assumed to be quantum fluctuations in the spatial and momentum coordinates, and mental action is assumed to work by ordering such fluctuations. It is shown that when the cumulative values of such fluctuations in a mean free path of a molecule are magnified by molecular interaction at the end of that path, the momentum of a molecule can (...) be changed from its original direction to any other direction. In this way mental action can produce effects through the ordering of thermal motions. Examples are given which show that the ordering of 10^4 10^5 molecules is sufficient to (a) produce detectible PK results and (b) open sufficient ion channels in the brain to initiate a physical action. The relationship of the above model to the arrow of time is discussed. (shrink)

It is assumed that mental action, such as free will, exists, and an exploration is made of its relationship to the brain, physical laws, and evolutionary selection. If the assumption is made that all content of conscious experience is encoded in the brain, it follows that free will must act as process only. This result is consistent with the experimental results of Libet and others that if free will exists, it must act by making a selection between alternatives provided by (...) the brain. Also, proposals for some additional actions of consciousness, besides free will, are reviewed. The use of mental action by consciousness is not in accord with presently known physics, in which physical changes are either deterministic or random, and an extension would have to be made to known physics to account for physical changes produced by such an action. However, such an extension could be fairly simple in overview, such as the assumption that consciousness can produce the ordering of randomness. Examples of several such theories are given. If consciousness can make selections among programs in the brain/nervous system, and thereby contribute to the formation of behavior, less programming would be needed, especially in situations affected by a variety of types of factors. For this reason consciousness might be present early in the evolutionary line for animals that explore new territory. Emotions and cognitive ability, even though determined by the brain, could be viewed as “choice guiders,” and for this reason their presence in an animal would indicate the presence of consciousness. (shrink)

It is not known whether consciousness can affect the physical world, as a result of a free will action or in some other way. To do so, it must be able to produce physical changes that cannot be accounted for by physical laws, an ability we will refer to as causal action, and several issues relevant to this possibility are discussed. 1) Until recently it was thought that the conservation laws of physics would prohibit causal action. It has now been (...) found that such is not the case, but other problems remain. 2) Observations of brain activity show that most of the process for determining a decision is done by the brain. However, the question of whether the final determination is done by mind or the brain is still open. The issue then arises that given the large amount of processing the brain can do, why would mind do this final step and if it does, why would the amount done by mind be so small? (shrink)

The concept of free will is central to our lives, as we make day-to-day decisions, and to our culture, in our ethical and legal systems. The very concept implies that what we choose can produce a change in our physical environment, whether by pressing a switch to turn out electric lights or choosing a long-term plan of action which can affect many people. Yet volition is not a part of presently known physical laws and it is not even known whether (...) it exists -- no physics experiments have ever established its presence. The purpose of this article is to make two points: first, that free will cannot be accounted for by presently known physical laws and second, that if free will exists, any description of its effects in the physical world would necessarily constitute a radical addition to presently known physical laws. (shrink)

It is shown that entropy increase in thermodynamic systems can plausibly be accounted for by the random action of vacuum radiation. A recent calculation by Rueda using stochastic electrodynamics (SED) shows that vacuum radiation causes a particle to undergo a rapid Brownian motion about its average dynamical trajectory. It is shown that the magnitude of spatial drift calculated by Rueda can also be predicted by assuming that the average magnitudes of random shifts in position and momentum of a particle correspond (...) to the lower limits of the uncertainty relation. The latter analysis yields a plausible expression for the shift in momentum caused by vacuum radiation. It is shown that when the latter shift in momentum is magnified in particle interactions, the fractional change in each momentum component is on the order of unity within a few collision times, for gases and (plausibly) for denser systems over a very broad range of physical conditions. So any system of particles in this broad range of conditions would move to maximum entropy, subject to its thermodynamic constraints, within a few collision times. It is shown that the spatial drift caused by vacuum radiation, as predicted by the above SED calculation, can be macroscopic in some circumstances, and an experimental test of this effect is proposed. Consistency of the above results with quantum mechanics is discussed, and it is shown that the diffusion constant associated with the above Brownian drift is the same as that used in stochastic interpretations of the Schrödinger equation. (shrink)

This essay examines the funeral sermon given by the Baptist theologian Andrew Fuller (1754–1815) for his friend and deacon Beeby Wallis in 1792 as a vantage-point from which to pursue reflection on Fuller’s concept of heaven and the beatific vision. The sermon has two main themes: the rest and rewards of those who die in Christ. The essay examines how Fuller interprets both of these phrases and then, looking at the rest of Fuller’s corpus, notes that ultimately God himself is (...) the believer’s reward. (shrink)

This article addresses the ability of Parallel Distributed Processing (PDP) networks to generate stagewise cognitive development in accordance with Piaget's theory of cognitive epigenesis. We carried out a replication study of the simulation experiments by McClelland (1989) and McClelland and Jenkins (1991) in which a PDP network learns to solve balance scale problems. In objective tests motivated from catastrophe theory, a mathematical theory of transitions in epigenetical systems, no evidence for stage transitions in network performance was found. It is concluded (...) that PDP networks lack the ability to recover the positive outcomes of analogous catastrophe analyses of real cognitive developmental data. In an attempt to further characterize the learning behaviour of PDP networks, we carried out a second simulation study using the discrimination‐shift paradigm. The results thus obtained indicate that PDP learning is compatible with the learning of stimulus‐response relationships, not with the acquisition of mediating rules such as conceived in (neo‐)Piagetian theory. In closing, we speculate about the feasibility of simulating stagewise development with alternative network architectures. (shrink)

Interest in science and math plays an important role in encouraging STEM motivation and career aspirations. This interest decreases for girls between late childhood and adolescence. Relatedly, positive mentoring experiences with female teachers can protect girls against losing interest. The present study examines whether visitors to informal science learning sites differ in their expressed science and math interest, as well as their science and math stereotypes following an interaction with either a male or female educator. Participants were visitors to one (...) of four ISLS in the United States and United Kingdom. Following an interaction with a male or female educator, they reported their math and science interest and responded to math and science gender stereotype measures. Female participants reported greater interest in math following an interaction with a female educator, compared to when they interacted with a male educator. In turn, female participants who interacted with a female educator were less likely to report male-biased math gender stereotypes. Self-reported science interest did not differ as a function of educator gender. Together these findings suggest that, when aiming to encourage STEM interest and challenge gender stereotypes in informal settings, we must consider the importance of the gender of educators and learners. (shrink)